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Anti-Interleukin-11 antibody produced in goat
产品编号: | 3370078 |
规格: | IgG fraction of antiserum, lyophilized powder |
包装规格: | 1 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Interleukin-11 antibody produced in goat
Anti-IL-11
基本信息
MDL number | MFCD00212981 |
NACRES | NA.41 |
General description【一般描述】 | Interleukin-11 (IL-11) is a pleotropic cytokine that belongs to the IL-6 family. The effects of IL-11 include hemopoiesis, macrophage differentiation and thrombopoiesis. Many cell types including osteoblasts, trophoblasts, fibroblasts, chondrocytes and a variety of tissue such as brain, gut, spinal cord and testis secrete IL-11. The cellular effects of IL-11 are mediated by a multimeric complex consisting of IL-11Rα and gp130Rβ subunits. The pathways activated by IL-11 include JAK/STAT, Ras/MAPK and Grb2 signaling. IL-11 plays a major role in inflammatory responses, immune responses by regulating the production of IgG by B cells and in tumorigenesis-related inflammation Anti-Interleukin-11 antibody specifically reacts with human IL-11. |
Specificity【特异性】 | The antibody neutralizes the biological activity of recombinant human IL-11. |
Immunogen【免疫原】 | recombinant human IL-11 expressed in Sf 21 insect cells. |
Application【应用】 | Anti-Human IL-11 is suitable for neutralization reactions. |
Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline. |
Preparation Note【制备说明】 | Purified using protein G. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | goat |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | IgG fraction of antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | lyophilized powder |
species reactivity | human |
technique(s) | neutralization: suitable |
UniProt accession no.【UniProt登记号】 | P20809 |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... IL11(3589) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |