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Anti-Interferon-γ Receptor 1 (IFN-γ R1) antibody produced in goat
产品编号: | 3370071 |
规格: | affinity isolated antibody, lyophilized powder |
包装规格: | 0.1 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
基本信息
MDL number | MFCD03455331 |
General description【一般描述】 | Human Interferon-γ- Receptor I (IFN-γ RI) is a 25kD, 227 amino acid residue containing protein that belongs to type II cytokine receptor family. IFN-γ RI has a crucial role in ligand-binding and signaling. Ligand IFN-γ induces tyrosine phosphorylation in IFN-γ RI which in turn leads to the formation of a docking site on the activated receptor for Stat1 that specifically activates IFN-γ induced gene transcription. Anti-Interferon γ Receptor I (IFN-γ RI) antibody can be used in neutralization assay using a confluent culture of HeLa cells. Goat anti-Interferon γ Receptor I (IFN-γ RI) antibody reacts specifically with recombinant human IFN-γ RI. The product has shown no cross-reactivity for recombinant human IFN-γ RII. |
Immunogen【免疫原】 | recombinant human IFN-γ Receptor I extracellular domain expressed in NSO cells. |
Application【应用】 | Anti-Interferon γ Receptor I (IFN-γ RI) antibody can be used in indirect ELISA and western blot. |
Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | goat |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | lyophilized powder |
species reactivity | human |
technique(s) | immunocytochemistry: 5-15 μg/mL using immersion fixed human peripheral blood mononuclear cells neutralization: suitable western blot: 0.1 μg/mL |
isotype【同位素/亚型】 | IgG |
UniProt accession no.【UniProt登记号】 | P15260 |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... IFNGR1(3459) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |