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Anti-HMBS (AB2) antibody produced in rabbit
产品别名
Anti-HMBS (AB2) antibody produced in rabbit
Anti-hydroxymethylbilane synthase
Anti-PBGD
Anti-UPS
Anti-PBG-D
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 40 kDa |
| species reactivity | human, guinea pig, rabbit, rat |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_000181 |
| UniProt accession no.【UniProt登记号】 | P08397 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... HMBS(3145) |
基本信息
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human HMBS |
| Application【应用】 | Anti-HMBS (AB2) antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL. |
| Biochem/physiol Actions【生化/生理作用】 | HMBS (hydroxymethylbilane synthase) gene encodes a protein that belongs to hydroxymethylbilane synthase superfamily and is expressed in erythroid cells. It is a cytosolic enzyme that plays a crucial role in heme biosynthetic pathway for catalyzing the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane.Defects in PBGD gene leads to cross-reacting immunological material (CRIM) positive forms of acute intermittent porphyria (AIP). |
| Sequence【序列】 | Synthetic peptide located within the following region: SSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQR |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
