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Anti-HMBOX1 antibody produced in rabbit
产品别名
Anti-HMBOX1 antibody produced in rabbit
Anti-Homeobox containing 1
基本信息
NACRES | NA.41 |
General description【一般描述】 | HMBOX1 is a homeobox transcription factor that may be involved in tumorigenesis. Studies have reported that this protein associates with telomeric double-stranded DNA and binds to nuclear bodies of promyelocytic leukemia. Rabbit Anti-HMBOX1 antibody recognizes chicken, canine, zebrafish, human, mouse, and rat HMBOX1. |
Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human HMBOX1 |
Application【应用】 | Rabbit Anti-HMBOX1 antibody is suitable for western blot applications at a concentration of 2.5 μg/ml. |
Biochem/physiol Actions【生化/生理作用】 | HMBOX1 is located at the boundary of 8p12.3 and 8p21.1. HMBOX1 proteins are highly conserved in human, mouse, rat, chicken and Xenopus laevis. Functional HMBOX1::EGFP (enhanced green fluorescent protein) fusion protein revealed that HMBOX1 accumulated more in cytoplasm than in nucleus. HMBOX1 is a transcription repressor. Human HMBOX1 is widely expressed in 18 tissues, and it is highly expressed in pancreas. Hmbox1 is widely expressed in mouse pancreas and the expression of this gene can also be detected in pallium, hippocampus and hypothalamus. |
Sequence【序列】 | Synthetic peptide located within the following region: ETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDK |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | IgG fraction of antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 47 kDa |
species reactivity | rat, horse, guinea pig, dog, mouse, rabbit, human, bovine |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_001129198 |
UniProt accession no.【UniProt登记号】 | Q6NT76 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... HMBOX1(79618) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |