您的位置：首页 > 产品中心 > Anti-FGFRL1 antibody produced in rabbit
Anti-FGFRL1 antibody produced in rabbit
| 产品编号： | 3362448 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-FGFRL1 antibody produced in rabbit
FGFR5
FGFRL1
FHFR
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 150 and 476 (Q8N441) of FGFR5 according to NP_001004356 |
| Application【应用】 | Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Biochem/physiol Actions【生化/生理作用】 | The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq] |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable western blot: 500-3000 |
| NCBI accession no.【NCBI登记号】 | NP_001004356 |
| UniProt accession no.【UniProt登记号】 | Q8N441 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... FGFRL1(53834) |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H317 - H412 |
| Precautionary Statements | P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313 |
| Hazard Classifications【危险分类】 | Aquatic Chronic 3 - Skin Sens. 1 |
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
