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Anti-FBP1 antibody produced in rabbit
| 产品编号： | 3361884 |
| 规格： | purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-FBP1 antibody produced in rabbit
FBP
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Fructose-1,6-bisphosphatase 1 (FBP1) gene is located on human chromosome 9q22.32. FBP1 is an allosteric enzyme, which is regulated by different enzymes. It has two isozymes, expressed in liver and muscle. |
| Immunogen【免疫原】 | FBP1 (NP_000498.2, 1 a.a. ~ 338 a.a) full-length human protein. Sequence MADQAPFDTDVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHSAQ |
| Biochem/physiol Actions【生化/生理作用】 | Fructose-1,6-bisphosphatase 1 (FBP1) deficiency is an inherited autosomal recessive disease. FBP1 is important in the carcinogenesis of different cancers. It promotes chemoresistance in cervical cancer. FBP1 is a tumor suppressor, which is downregulated in cancers. It regulates the Wnt/β-Catenin pathway in breast cancer. |
| Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 36.8 kDa |
| species reactivity | human, mouse |
| technique(s) | western blot: 1 μg/mL |
| NCBI accession no.【NCBI登记号】 | NM_000507 |
| UniProt accession no.【UniProt登记号】 | P09467 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... FBP1(2203) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
