1,2,3,4-四氢-9H-吡啶并[3,4-b]吲哚

C₁₁H₁₂N₂

172.23

MFCD00004954

24857939

NA.22

Ozonolysis of the enamine bond of 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole derivatives was studied.

用于生物碱的合成以及用于研究神经退行性疾病。

• Reactant for synthesis of the indolyl-β-carboline alkaloid eudistomin U via IBX mediated room temperature oxidative aromatization
• Reactant for preparation of neuroprotective HDAC6 inhibitors
• Reactant for preparation of aminofuranopyrimidines as EGFR and Aurora A kinase inhibitors
• Reactant for preparation of inhibitors of CDK4
• Reactant for preparation of tetrahydrocarboline derivatives of as human 5-HT5A receptor ligands
• Reactant for preparation of 5-(diaminomethyl)-2,4-aminopyrimidines as dihydrofolate reductase inhibitors and antibacterial agents

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 300764.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

100

98%

206-208 ℃ (lit.)

C1Cc2c(CN1)[nH]c3ccccc23

1S/C11H12N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-4,12-13H,5-7H2

CFTOTSJVQRFXOF-UHFFFAOYSA-N

rat ... Htr2a(29595), Htr2c(25187)

1, 5 g in glass bottle

GHS07

Warning

H315 - H319 - H335

P302 + P352 - P305 + P351 + P338

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Respiratory system

11 - Combustible Solids

WGK 3

dust mask type N95 (US), Eyeshields, Gloves