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Anti-EPHA10 antibody produced in rabbit
产品编号: | 3360194 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-EPHA10 antibody produced in rabbit
Anti-EPH receptor A10
Anti-Ephrin type-A receptor 10
Anti-FLJ16103
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | EphA10 antibody was raised against a 14 amino acid peptide of near the amino terminus of human EphA10. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP3500068. |
Physical form【外形】 | Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | rat, mouse, human |
technique(s) | indirect ELISA: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_001092909 |
UniProt accession no.【UniProt登记号】 | Q5JZY3 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... EPHA10(284656) |
产品说明
Target description【目标描述】 | Eph receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell–cell communication regulating cell attachment, shape, and mobility of neuronal and endothelial cells in central nervous system function and in development. Eph receptors can be divided into two subgroups: EphA and EphB. In mammals, the EphA class consists of eight members (EphA 1-7 and 10) that in general bind to ephrin-A members linked to the cell membrane through a glycosylphosphatidylinositol linkage. The EphB class consists of six members (EphB 1-6) that in general bind ephrin-B members that transverse the cell membrane. The Ephrin / EPH signaling pathway networks with the WNT signaling pathway during embryogenesis, tissue regeneration, and carcinogenesis. Recent studies show that Eph/EFN might be relevant in normal B-cell biology and could represent new potential prognostic markers and therapeutic targets for CLL. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |