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Anti-Dopamine Transporter, Extracellular Loop 2 antibody produced in rabbit
产品编号: | 3358262 |
规格: | affinity isolated antibody, buffered aqueous glycerol solution |
包装规格: | 1 VIAL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Dopamine Transporter, Extracellular Loop 2 antibody produced in rabbit
Anti-DAT
基本信息
MDL number | MFCD02262815 |
NACRES | NA.41 |
Immunogen【免疫原】 | synthetic peptide from the extracellular loop 2 region of human dopamine transporter. |
Application【应用】 | Anti-Dopamine Transporter, Extracellular Loop 2 antibody produced in rabbit is suitable at a working dilution of 1:1000 for western blotting using SDS-solubilized human striatal samples and for immunohistochemistry using formaldehyde-fixed human and monkey brain sections. |
Biochem/physiol Actions【生化/生理作用】 | The dopamine transporter (DAT1) acts to take released dopamine back up into presynaptic terminals and has been implicated in human disorders such as parkinsonism, Tourette syndrome, and substance abuse. DAT1 gene is a primary target gene for ADHD (Attention deficit hyperactivity disorder). DAT polymorphism along with maternal prenatal smoking is associated with childhood hyperactivity-impulsivity and inattentiveness. |
Physical form【外形】 | Solution in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA, and 50% glycerol. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous glycerol solution |
species reactivity | human, monkey |
technique(s) | immunohistochemistry: 1:1,000 using formaldehyde-fixed human and monkey brain sections western blot: 1:1,000 using SDS-solubilized human striatal samples |
UniProt accession no.【UniProt登记号】 | Q01959 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... SLC6A3(6531) |
产品说明
Target description【目标描述】 | The dopamine transporter (DAT1) acts to take released dopamine back up into presynaptic terminals and has been implicated in human disorders such as parkinsonism, Tourette syndrome, and substance abuse. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |