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Anti-DNALI1 antibody produced in rabbit
产品别名
Anti-DNALI1 antibody produced in rabbit
Anti-Dynein, axonemal, light intermediate chain 1
Anti-dJ423B22.5
Anti-hp28
Anti-P28
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human DNALI1 |
Application【应用】 | Anti-DNALI1 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL. |
Biochem/physiol Actions【生化/生理作用】 | DNALI1 (dynein, axonemal, light intermediate chain 1) gene encodes a 258 amino acid containing protein that belongs to inner dynein arm light chain family. They are large microtubule-based motor protein complexes generating the force for the movement of eukaryotic cilia and flagella. The human hp28 (DNALI1) is localized on chromosome 1 region p35 and is predominantly expressed in spermatids. Dnali1 protein is also present in cilia of the trachea as well as in flagella of mature sperm and hence facilitates as axonemal dynein. It also has a role in the ciliary and flagellar motility. Homologous mutation in DNALI1 gene leads to situs inversus and primary ciliary dyskinesia (Kartagener Syndrome). Defect in DNALI1 gene also results in potential candidate for immotile cilia syndrome (ICS). |
Sequence【序列】 | Synthetic peptide located within the following region: ALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVE |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 31 kDa |
species reactivity | guinea pig, horse, mouse, rat, rabbit, human, bovine, dog |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_003453 |
UniProt accession no.【UniProt登记号】 | O14645 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... DNALI1(7802) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |