您的位置:首页 > 产品中心 > Anti-DIDO1 (AB3) antibody produced in rabbit
Anti-DIDO1 (AB3) antibody produced in rabbit
产品别名
Anti-DIDO1 (AB3) antibody produced in rabbit
Anti-DATF1
Anti-C20orf158
Anti-BYE1
Anti-DIO-1
Anti-Death inducer-obliterator 1
Anti-DIDO2
Anti-DIDO3
Anti-DIO1
基本信息
NACRES | NA.41 |
General description【一般描述】 | Death inducer-obliterator 1 (DIDO1) is known to be a BMP-target gene and is involved in melanoma progression. It has also been implicated in colorectal carcinogenesis. Rabbit Anti-DIDO1 antibody recognizes human, mouse, rat, canine, chicken, bovine, and zebrafish DIDO1. |
Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human DIDO1 |
Application【应用】 | Rabbit Anti-DIDO1 antibody is suitable for western blotting applications at a concentration of 1 μg/ml. |
Biochem/physiol Actions【生化/生理作用】 | In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. DIDO1 gene is similar to the mouse gene and therefore is thought to be involved in apoptosis.Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms. |
Sequence【序列】 | Synthetic peptide located within the following region: KKAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 61 kDa |
species reactivity | rat, rabbit, human, mouse |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_071388 |
UniProt accession no.【UniProt登记号】 | Q9BTC0 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... DIDO1(11083) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |