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Anti-COX41 antibody produced in rabbit
产品别名
Anti-COX41 antibody produced in rabbit
COX IV-1
COXIV
Cytochrome c oxidase polypeptide IV
COX4
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | COX41 (cytochrome c oxidase subunit 4I1) is located on human chromosome 16q24. COX4NB (COX4 neighbour) and COX4I1 (COX4 isoform 1) belongs to the cytochrome C oxidase subunit IV (COX4) family. Anti-COX41 Antibody detects endogenous levels of total COX41 protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human COX41. Immunogen Range: 11-60 |
| Biochem/physiol Actions【生化/生理作用】 | COX4 isoform 1 (COX4-1) (COX4-1) may play an important role in glioma chemoresistance. It regulates the upregulation of BMI1 (polycomb complex protein BMI1). It is necessary for the multiplication of GBM (glioblastoma multiforme). In cells, expression of COX4-1 is necessary to maintain the stability of mitochondria and ROS (reactive oxygen species) homeostasis. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 19 kDa |
| species reactivity | human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:20000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | P13073 |
| UniProt accession no.【UniProt登记号】 | P13073 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... COX4I1(1327) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
