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Anti-COPS2 antibody produced in rabbit
产品别名
Anti-COPS2 antibody produced in rabbit
Anti-COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | COPS2 forms a part of the COP9 signalosome. Rabbit Anti-COPS2 antibody recognizes human, mouse, and rat COPS2. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human COPS2 |
| Application【应用】 | Rabbit Anti-COPS2 antibody can be used for western blot applications at a concentration of 0.5 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1. |
| Sequence【序列】 | Synthetic peptide located within the following region: MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAA |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 51 kDa |
| species reactivity | rabbit, bovine, guinea pig, mouse, human, horse, rat, dog |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001137359 |
| UniProt accession no.【UniProt登记号】 | P61201 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... COPS2(9318) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
