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Anti-CHP2 antibody produced in rabbit
产品别名
Anti-CHP2 antibody produced in rabbit
Hepatocellular carcinoma-associated antigen 520
Calcineurin B homologous protein 2
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Anti-CHP2 antibody detects endogenous levels of total CHP2 protein. The CHP2 (calcineurin like EF-hand protein 2) gene is mapped to human chromosome 16p12.2. It encodes a 23kDa protein containing myristoylation site at its N-terminal and four EF-hand Ca2+ binding motifs. The gene is predominantly expressed in small intestine and cancer cells. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human CHP2. Immunogen Range: 101-150 |
| Biochem/physiol Actions【生化/生理作用】 | The protein encoded by CHP2 (calcineurin like EF-hand protein 2) gene serves as an important cofactor of Na+/H+ exchanger isoform 1 and maintains high intracellular pH in cancer cells. CHP2 protects cells from dying due to serum deprivation. Overexpression of the gene is observed in ovarian cancer and it is involved in the growth, proliferation, invasion and metastasis of cancer cells. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 22 kDa |
| species reactivity | rat, mouse, human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:40000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | O43745 |
| UniProt accession no.【UniProt登记号】 | O43745 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CHP2(63928) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
