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ANTI-CD45(C-TERMINAL) antibody produced in rabbit
| 产品编号： | 3352173 |
| 规格： | IgG fraction of antiserum, buffered aqueous solution |
| 包装规格： | 400 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
ANTI-CD45(C-TERMINAL) antibody produced in rabbit
CD45
Leukocyte common antigen
T200
PTPRC
Receptor-type tyrosine-protein phosphatase C
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Protein tyrosine phosphatase, receptor type C (PTPRC) or leucocyte common antigen CD45 is expressed on T-cells and is found in multiple isoforms. The extracellular domain of the protein is predicted to have an amino-terminal mucin-like segment, a cysteine-rich domain and three fibronectin type 3 domains. The gene encoding this protein is localized on human chromosome 1q31.3. |
| Application【应用】 | ANTI-CD45(C-TERMINAL) antibody produced in rabbit has been used in Western blotting. |
| Biochem/physiol Actions【生化/生理作用】 | Protein tyrosine phosphatase, receptor type C (PTPRC) or leucocyte common antigen CD45 acts as a protein tyrosine phosphatase in leucocyte signaling. It has a role in flow cytometric diagnostics in leukemia. By dephosphorylation of Src kinases, the protein acts as a regulator of antigen receptor signaling in T and B cells. As a negative regulator of janus kinases, CD45 inhibits cytokine receptor signaling. |
| Physical form【外形】 | Supplied in PBS with 0.09% (W/V) sodium azide |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 147254 Da |
| species reactivity | human |
| technique(s) | flow cytometry: 1:10-1:50 immunohistochemistry: 1:10-1:50 western blot: 1:1000 |
| NCBI accession no.【NCBI登记号】 | NP_002829.3 |
| UniProt accession no.【UniProt登记号】 | P08575 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PTPRC(5788) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
