Anti-CD22 antibody produced in rabbit

NA.41

The antibody detects endogenous level of total CD22 protein.

Peptide sequence around aa. 839-843 (N-V-D-Y-V), according to the protein NP_001762.2

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

rabbit

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

~140 kDa

human

1 mg/mL

western blot: 1:500-1:1000

IgG

(N-V-D-Y-V)

NM_001771.3

P20273

wet ice

−20℃

human ... CD22(933)

Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

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12 - Non Combustible Liquids

WGK 1