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Anti-Caspase-12 (small) antibody produced in rabbit
产品编号: | 3351016 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Caspase-12 (small) antibody produced in rabbit
Anti-Caspase 12
基本信息
MDL number | MFCD03454855 |
NACRES | NA.41 |
General description【一般描述】 | Caspase-12 (CASP12) is an immunomodulatory factor, that is present in the cytoplasmic side of the ER (endoplasmic reticulum). It is upregulated highly in muscle, liver and kidney. |
Immunogen【免疫原】 | a synthetic peptide corresponding to amino acids within the small cleavage product of murine caspase-12. |
Biochem/physiol Actions【生化/生理作用】 | Caspase-12 (CASP12) plays an important role in endoplasmic reticulum (ER)-related apoptosis. It moderates hepatocyte apoptosis prompted by carbon tetrachloride. Lack of caspase-12 (CASP12) increases cytokine responses. |
Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP3197. |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide |
产品性质
biological source【生物来源】 | rabbit |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | predicted mol wt 46 kDa |
species reactivity | human, rat, mouse |
technique(s) | immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
UniProt accession no.【UniProt登记号】 | O08736 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | mouse ... Casp12(12364) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |