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Anti-Calcium Channel (β1 subunit) antibody produced in rabbit
产品编号: | 3350549 |
规格: | ~1 mg/mL, fractionated antiserum, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Calcium Channel (β1 subunit) antibody produced in rabbit
Anti-Voltage-dependent L-type calcium channel, β1 subunit
基本信息
MDL number | MFCD01633054 |
NACRES | NA.41 |
General description【一般描述】 | The gene CACNB1 (Calcium channel voltage-dependent subunit β 1) is mapped to human chromosome 17q11.2-q22. |
Immunogen【免疫原】 | synthetic peptide derived from the rat β1 calcium channel conjugated to KLH. |
Application【应用】 | Anti-Calcium Channel (β1 subunit) antibody produced in rabbit is suitable for western blot at a concentration of 5-10 μg/mL using rat brain tissue lysate |
Biochem/physiol Actions【生化/生理作用】 | The CACNB1 (Calcium channel voltage-dependent subunit β 1) is an intracellular regulatory subunit of voltage-activated calcium channels that has significant impact on membrane expression and electrophysical characteristics of the channel. Calcium channel β subunits regulate voltage-dependent calcium currents through direct interaction with α1 subunits. CACNB1 is a target of miRNA-328. In mouse model, CACNB1 is involved in gene expression in muscle progenitor cells and regulates skeletal muscle mass during embryonic development by suppressing myogenin. |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.08% sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | fractionated antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human, rat, mouse |
concentration【浓度】 | ~1 mg/mL |
technique(s) | western blot: 5-10 μg/mL using rat brain tissue lysate |
UniProt accession no.【UniProt登记号】 | Q02641 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... CACNB1(782) mouse ... Cacnb1(12295) rat ... Cacnb1(50688) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |