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Anti-BMP2K antibody produced in rabbit
产品别名
Anti-BMP2K antibody produced in rabbit
Anti-DKFZp434P0116
Anti-BMP2 inducible kinase
Anti-BIKE
Anti-DKFZp434K0614
Anti-HRIHFB2017
基本信息
NACRES | NA.41 |
General description【一般描述】 | BMP2 inducible kinase (BMP2K) is a 126 kDa protein. The protein is also recognized as clathrin-coated vesicle-associated protein. BMP2K gene is located on human chromosome 4q21.21. |
Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human BMP2K |
Biochem/physiol Actions【生化/生理作用】 | BMP2 inducible kinase (BMP2K) is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. BMP2K is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Two transcript variants encoding different isoforms have been found for this gene. BMP2K contributes to phosphorylation of myelin basic protein. The protein is important in protein-protein interactions. BMP2K is linked to myopia. It is a potential target for treating human immunodeficiency virus (HIV). |
Sequence【序列】 | Synthetic peptide located within the following region: VKVLAPGEFGNHRPKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGD |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 74 kDa |
species reactivity | yeast, guinea pig, mouse, human |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
UniProt accession no.【UniProt登记号】 | Q4W5H2 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... BMP2K(55589) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |