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Anti-AURA antibody produced in rabbit
产品别名
Anti-AURA antibody produced in rabbit
AIK
ARK1
Aurora-family kinase 1
Aurora-related kinase 1
Aurora-A
产品性质
biological source【生物来源】 | rabbit |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen 45 kDa |
species reactivity | human, rat, mouse |
concentration【浓度】 | ~1 mg/mL |
technique(s) | ELISA: 1:5000 western blot: 1:500-1:1000 |
NCBI accession no.【NCBI登记号】 | O14965 |
UniProt accession no.【UniProt登记号】 | O14965 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... AURKA(6790) |
基本信息
General description【一般描述】 | AURA/AURKA (aurora kinase A) is mapped on to human chromosome 20q13.2. It is also termed as STK15 (serine/threonine kinase 15). This gene codes for a protein of 403 amino acids with regulatory and catalytic domains. |
Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human AurA. Immunogen Range: 311-360 |
Biochem/physiol Actions【生化/生理作用】 | AURA/AURKA (aurora kinase A) modulates cell cycle checkpoints and plays important roles in centrosome division, cytoskeleton and cytokinesis. It sustains the integrity of chromosome after DNA damage. The catalytic domain of AURKA possesses a serine/threonine kinase activity role. It is overexpressed in several malignancies like invasive carcinomas of ovary, head, neck and breast. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |