Anti-ARFGEF2 antibody produced in rabbit

NA.41

ADP ribosylation factor guanine nucleotide exchange factor 2 (ARFGEF2) possesses a Sec7 domain which is crucial for its activity. This protein is expressed in the brain and the gene encoding it is localized on human chromosome 20.

The antibody detects endogenous levels of total ARFGEF2 protein.

Synthetic peptide corresponding to a region derived from internal residues of human ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)

ADP ribosylation factor guanine nucleotide exchange factor 2 (ARFGEF2) activates ADP-ribosylation factors (ARFs) by exchanging guanosine diphosphate (GDP) with guanosine triphosphate (GTP). It aids in the release of type I tumor necrosis factor receptor (TNFR1) from human umbilical vein endothelial cells. Mutation in the ARFGEF2 gene has been linked to microcephaly and periventricular heterotopia.

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Rabbit IgG in pH7.3 PBS, 0.05% NaN₃, 50% Glycerol.

rabbit

100

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

202 kDa

mouse, human

3.4 mg/mL

immunohistochemistry: 1:50- 1:200
western blot: 1:200-1:1000 (Cell Lysate)

IgG

NP_006411.2

Q9Y6D5

wet ice

−20℃

human ... ARFGEF2(10564)

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12 - Non Combustible Liquids

WGK 1