您的位置:首页 > 产品中心 > Anti-AKT antibody produced in rabbit
Anti-AKT antibody produced in rabbit
产品别名
Anti-AKT antibody produced in rabbit
AKT1 kinase
AKT
PKB
kinase Akt1
C-AKT
基本信息
MDL number | MFCD03096597 |
NACRES | NA.41 |
General description【一般描述】 | AKT1 (AKT serine/threonine kinase 1) is also called as v-akt murine thymoma viral oncogene homolog 1 and PKBα(protein kinase B). It is upregulated in liver, muscle and adipocytes. AKT1 gene is mapped to human chromosome 14q32. It is a member of AKT family that has an amino-terminal pleckstrin homology (PH) domain, a short α-helical linker and a carboxyl-terminal kinase domain. Anti-AKT Antibody detects endogenous levels of total AKT protein. |
Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human Akt. Immunogen Range: 292-341 |
Application【应用】 | Anti-AKT1 (Ab-473) antibody has been used in western blotting and immunostaining. |
Biochem/physiol Actions【生化/生理作用】 | AKT1 (AKT serine/threonine kinase 1) controls the survival of cell and anti-apoptotic actions that attack the pathogenesis of several cancers , hence it plays a crucial role in tumorigenesis. In mice, AKT1 is essential for normal development. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
biological source【生物来源】 | rabbit |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen 55 kDa |
species reactivity | mouse, rat, human |
concentration【浓度】 | ~1 mg/mL |
technique(s) | ELISA: 1:20000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
NCBI accession no.【NCBI登记号】 | P31749 |
UniProt accession no.【UniProt登记号】 | P31749 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... AKT1(207) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |