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Anti-ADAM23 antibody produced in chicken
产品编号: | 3343306 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 50 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-ADAM23 antibody produced in chicken
Anti-A disintegrin and metalloproteinase domain 23
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Immunogen Sequence: GI # 4501913, sequence 72-144 Recombinant ADAM metallopeptidase domain 23 preproprotein |
Application【应用】 | Anti-ADAM23 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. |
Biochem/physiol Actions【生化/生理作用】 | Disintegrin and metalloproteinase domain-containing protein 23 is an enzyme encoded by the ADAM23 gene in humans and is a member of a disintegrin and metalloprotease (ADAM) family. It is higly expressed in the brain and may function as integrin ligands in the brain along with other proteins. ADAM23 is associated with the progression of non-small-cell lung carcinoma (NSCLC) and its downregulation may be correlated with promoter methylation. It may be down-regulated by aberrant promoter hypermethylation during the progression of colorectal cancer. ADAM23 is down-regulated by methylation in brain tumors, which is a rare event. |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
biological source【生物来源】 | chicken |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
manufacturer/tradename | Genway 15-288-21429 |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_003803.1 |
UniProt accession no.【UniProt登记号】 | O75077 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... ADAM23(8745) |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |