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Anti-ACOT13 antibody produced in mouse
产品编号: | 3342968 |
规格: | purified immunoglobulin, buffered aqueous solution |
包装规格: | 50 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-ACOT13 antibody produced in mouse
HT012
MGC4961
PNAS-27
基本信息
NACRES | NA.41 |
General description【一般描述】 | This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene |
Immunogen【免疫原】 | ACOT13 (NP_060943.1, 1 a.a. ~ 140 a.a) full-length human protein. Sequence MTSMTQSLREVIKAMTKARNFERVLGKITLVSAAPGKVICEMKVEEEHTNAIGTLHGGLTATLVDNISTMALLCTERGAPGVSVDMNITYMSPAKLGEDIVITAHVLKQGKTLAFTSVDLTNKATGKLIAQGRHTKHLGN |
Application【应用】 | Anti-ACOT13 antibody produced in mouse is suitable for western blot anaysis. |
Biochem/physiol Actions【生化/生理作用】 | ACOT13 (Acyl-CoA thioesterase 13) is highly involved in the regulation of hepatic lipid and glucose homeostasis. It maintains the intracellular concentration of hepatic free fatty acids (FFAs) and fatty acyl-CoAs under physiological conditions by forming a complex with phosphatidylcholine transfer protein (PC-TP). In liver, it controls the β-oxidation of fatty acids, which is highly crucial for entry of fatty acyl-CoAs into mitochondria. |
Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
产品性质
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen ~15 kDa |
species reactivity | human |
technique(s) | western blot: 1 μg/mL |
NCBI accession no.【NCBI登记号】 | NM_018473.2 |
UniProt accession no.【UniProt登记号】 | Q9NPJ3 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... ACOT13(55856) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 1 |