您的位置：首页 > 产品中心 > Anti-4E-BP1 antibody produced in rabbit
Anti-4E-BP1 antibody produced in rabbit
产品别名
Anti-4E-BP1 antibody produced in rabbit
Eukaryotic translation initiation factor 4E binding protein 1
EIF4EBP1
4EBP1
Insulin-stimulated EIF-4E binding protein PHAS-I
P/OKCL.6
基本信息
| MDL number | MFCD04040379 |
| NACRES | NA.41 |
| General description【一般描述】 | Anti-4E-BP1 Antibody detects endogenous levels of total 4E-BP1 protein. The gene E1F4EBP1 (eukaryotic translation initiation factor 4E binding protein 1) is located on human chromosome 8p11. 4E-BP1 is a multifactor regulated multifunctional protein. It belongs to the translation repressor protein family. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human 4E-BP1. Immunogen Range: 30-79 |
| Application【应用】 | Anti-4E-BP1 antibody has been used in western blotting. |
| Biochem/physiol Actions【生化/生理作用】 | E1F4EBP1 (eukaryotic translation initiation factor 4E binding protein 1) is involved in protein synthesis, cell growth and survival. Phosphorylation of E1F4EBP1 releases it from eIF4E (eukaryotic translation initiation factor 4E), thereby resulting in cap-dependent translation. E1F4EBP1 is also involved in tumorigenesis and the gene is overexpressed in various carcinomas. It also serves as a substrate for mTORC1 (mammalian target of rapamycin complex 1). |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 12 kDa |
| species reactivity | rat, mouse, human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:5000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | Q13541 |
| UniProt accession no.【UniProt登记号】 | Q13541 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... EIF4EBP1(1978) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
