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A922500

产品编号:3336299
CAS NO:959122-11-3
包装规格:1 MG,5 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
33362991 MG747
33362995 MG3110
产品别名

959122-11-3

A922500

基本信息
Empirical Formula【经验(实验)分子式】
C26H24N2O4
Molecular weight
428.48
NACRES
NA.77
Application【应用】
A922500 has been used in the inhibition of diacylglycerol acyltransferase (DGAT) in epithelial human breast cancer cell line (MDA-MB-231), digitonin-permeabilized human cancer cells, human myotubes and macrophages.
Biochem/physiol Actions【生化/生理作用】
The diacylglycerol acyltransferase (DGAT) 1 inhibitor A922500 was shown to effectively reduce postprandial serum triglyceride levels in rodents at concentrations of 0.03, 0.3 and 3 mg/kg. These results suggest A922500 may have beneficial effects in reducing the risk of cardiovascular disease.
Diacylglycerol acyltransferase (DGAT-1) inhibitor; IC50 7 to 24 nM
Physical form【外形】
A922500 is supplied as a crystalline solid.
Preparation Note【制备说明】
A stock solution may be made by dissolving the A922500 in the solvent of choice. A922500 is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF).
产品性质
biological source【生物来源】
synthetic (organic)
Quality Level【质量水平】
100
Assay【测定】
>95% (HPLC)
form【形式】
powder
mol wt【分子量】
Mw 428.5
solubility【溶解性】
DMSO: 10 mg/mL, clear, colorless to greenish-yellow
storage temp.【储存温度】
−20℃
InChI key
BOZRFEQDOFSZBV-DHIUTWEWSA-N
packaging【包装】
1, 5, 10 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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