您的位置：首页 > 产品中心 > 444912-48-5， (R,S)-AM1241
(R,S)-AM1241
| 产品编号： | 3329125 |
| 规格： | ≥98% (HPLC), solid |
| CAS NO： | 444912-48-5 |
| 包装规格： | 5 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
444912-48-5
(R,S)-AM1241
(R,S)-3-(2-Iodo-5-nitrobenzoyl)-1-(1-methyl-2-piperidinylmethyl)-1H-indole
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C22H22IN3O3 |
| Molecular weight | 503.33 |
| MDL number | MFCD11045986 |
| PubChem Substance ID【PubChem化学物质编号】 | 24891092 |
| NACRES | NA.77 |
| Application【应用】 | (R,S)-AM1241 has been used as a cannabinoid CB2 agonist:
|
| Biochem/physiol Actions【生化/生理作用】 | AM1241 acts as an antinociceptive agent in several animal pain models. It has a potential to delay disease progression in amyotrophic lateral sclerosis (ALS) mouse model. Intrathecal, intravenous or intraperitoneal administration of AM1241 reduces hyperalgesia and allodynia in neuropathic rats. Selective CB2 cannabinoid receptor agonist |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| drug control | regulated under CDSA - not available from sigma-aldrich Canada |
| color【颜色】 | yellow |
| solubility【溶解性】 | DMSO: ~18 mg/mL at 60 ℃ |
| SMILES string | CN1CCCCC1Cn2cc(C(=O)c3cc(ccc3I)[N+]([O-])=O)c4ccccc24 |
| InChI | 1S/C22H22IN3O3/c1-24-11-5-4-6-16(24)13-25-14-19(17-7-2-3-8-21(17)25)22(27)18-12-15(26(28)29)9-10-20(18)23/h2-3,7-10,12,14,16H,4-6,11,13H2,1H3 |
| InChI key | ZUHIXXCLLBMBDW-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07,GHS08 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H315 - H319 - H334 - H335 |
| Precautionary Statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
