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(R)-DRF053 hydrochloride hydrate
产品别名
(R)-DRF053 hydrochloride hydrate
2-[[9-(1-Methylethyl)-6-[[3-(2-pyridinyl)phenyl]amino]- 9H-purin-2-yl]amino]-1-butanol hydrochloride hydrate
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H27N7O · xHCl · yH2O |
| Molecular weight | 417.51 (anhydrous free base basis) |
| MDL number | MFCD17215921 |
| PubChem Substance ID【PubChem化学物质编号】 | 329798839 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | DRF053 is a more potent version of roscovitine. It is 2 fold more potent against CDK5 (80 nM) and over 150 times more potent against CDK1 (14 nM). |
| Features and Benefits【特点和优势】 | This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | yellow |
| solubility【溶解性】 | DMSO: ≥30 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O.Cl.CC[C@H](CO)Nc1nc(Nc2cccc(c2)-c3ccccn3)c4ncn(C(C)C)c4n1 |
| InChI | 1S/C23H27N7O.ClH.H2O/c1-4-17(13-31)27-23-28-21(20-22(29-23)30(14-25-20)15(2)3)26-18-9-7-8-16(12-18)19-10-5-6-11-24-19;;/h5-12,14-15,17,31H,4,13H2,1-3H3,(H2,26,27,28,29);1H;1H2/t17-;;/m1../s1 |
| InChI key | ZOSNTFVWVJFXQO-ZEECNFPPSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H315 - H319 - H335 |
| Precautionary Statements | P261 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
