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5-碘-2′-脱氧尿苷
5-Iodo-2′-deoxyuridine
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3325834 | 5 G | 4180 | |||
3325834 | 25 G | 16640 |
产品别名
54-42-2
5-碘-2′-脱氧尿苷
5-Iodo-2′-deoxyuridine
IDU
IdUrd
2′-Deoxy-5-iodouridine
5-IUdR
1-(2-Deoxy-β-
Idoxuridine
5-HIAA
碘苷
2′-脱氧-5-碘尿苷
1-(2-脱氧-β-
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C9H11IN2O5 |
Molecular weight | 354.10 |
Beilstein | 30397 |
EC number【EC 号】 | 200-207-8 |
MDL number | MFCD00134656 |
PubChem Substance ID【PubChem化学物质编号】 | 57654307 |
NACRES | NA.51 |
Application【应用】 | 5-Iodo-2′-deoxyuridine has been used in molecular combing assay or DNA fiber assay. 5-碘-2′-脱氧尿苷(5-IUdR;IdUrd)是一种嘧啶类似物(卤代胸苷),具有抗牛痘病毒(正痘病毒)活性。 IdUrd在人类癌症研究中被用作放射增敏剂。 |
Biochem/physiol Actions【生化/生理作用】 | 5-Iodo-2′-deoxyuridine prevents in vitro DNA viral replication. This is observed in herpesviruses and poxviruses It might possess teratogenic, tumor-promoting, mutagenic, and immunosuppressive properties. 5-Iodo-2′-deoxyuridine, used in topical applications, is effective against epithelial infections. |
产品性质
Quality Level【质量水平】 | 200 |
Assay【测定】 | ≥99% (HPLC) |
form【形式】 | powder or crystals |
mp | 194 ℃ (lit.) |
solubility【溶解性】 | 1 N NH4OH: 50 mg/mL, clear to very slightly hazy, colorless to light yellow |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(I)C(=O)NC2=O |
InChI | 1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1 |
InChI key | XQFRJNBWHJMXHO-RRKCRQDMSA-N |
packaging【包装】 | 5, 25 g in glass bottle |
安全信息
Pictograms【象形图】 | GHS07,GHS08 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H315 - H319 - H335 - H341 - H361 |
Precautionary Statements | P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
Hazard Classifications【危险分类】 | Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3 |
Target Organs【靶器官】 | Respiratory system |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |