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4-Nitrophenyl 4-guanidinobenzoate hydrochloride

产品编号:3317245
规格:protease inhibitor and substrate
CAS NO:19135-17-2
包装规格:500 MG,1 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3317245500 MG3230
33172451 G5840
产品别名

19135-17-2

4-Nitrophenyl 4-guanidinobenzoate hydrochloride

NPGB

4-Guanidinobenzoic acid 4-nitrophenylester hydrochloride

pNPGB

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C14H12N4O4 · HCl
Molecular weight
336.73
Beilstein
8024554
EC number【EC 号】
242-831-3
MDL number
MFCD00037010
PubChem Substance ID【PubChem化学物质编号】
24897847
NACRES
NA.32
General description【一般描述】
4-Nitrophenyl 4-guanidinobenzoate hydrochloride (pNPGB) is a trypsin substrate. It is more water-soluble than 4-methylumbelliferyl 4-guanidinobenzoate and is preferred in spectrophotometric assay.
Application【应用】
4-Nitrophenyl 4-guanidinobenzoate hydrochloride has been used:
  • as a substrate for trypsin for active site titration experiments
  • for pre-treating of mosquito eggs in the interplasmid transposition assay
  • as a component of isotonic buffer to moisten filter paper for mosquito embryo collection

Biochem/physiol Actions【生化/生理作用】
4-Nitrophenyl 4-guanidinobenzoate hydrochloride (pNPGB) inhibits phenoloxidase enzyme and delays embryo chorionic membrane hardening.
产品性质
Quality Level【质量水平】
200
Assay【测定】
≥95.0% (TLC)
form【形式】
powder
solubility【溶解性】
formic acid: soluble 49.00-51.00 mg/mL
storage temp.【储存温度】
−20℃
SMILES string
Cl[H].NC(=N)Nc1ccc(cc1)C(=O)Oc2ccc(cc2)[N+]([O-])=O
InChI
1S/C14H12N4O4.ClH/c15-14(16)17-10-3-1-9(2-4-10)13(19)22-12-7-5-11(6-8-12)18(20)21;/h1-8H,(H4,15,16,17);1H
InChI key
PKSBDZOBYIKNGY-UHFFFAOYSA-N
packaging【包装】
1 g in glass bottle
500 mg in glass bottle
安全信息
Pictograms【象形图】
GHS05
Signal word【警示用语:】
Danger
Hazard Statements
H318
Precautionary Statements
P280 - P305 + P351 + P338
Hazard Classifications【危险分类】
Eye Dam. 1
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Gloves
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