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3-AP
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3293746 | 5 MG | 1068 | |||
3293746 | 25 MG | 3500 |
产品别名
143621-35-6
3-AP
3-Aminopyridine-2-carboxaldehyde thiosemicarbazone
PAN-811
基本信息
Empirical Formula【经验(实验)分子式】 | C7H9N5S |
Molecular weight | 195.24 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | 3-aminopyridine carboxaldehyde thiosemicarbazone (3-AP) has a IC50 value of 0.3μM. It exhibits anti-proliferative activity in preclinical models of cancer, such as lung cancer. It also has an ability to increase the cytotoxicity, intracellular uptake and DNA incorporation of gemcitabine in vitro. 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) is a ribonucleotide reductase inhibitor and iron chelator with anti-tumor activity. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to light brown |
solubility【溶解性】 | DMSO: 10 meq/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
InChI | 1S/C7H9N5S/c8-5-2-1-3-10-6(5)4-11-12-7(9)13/h1-4H,8H2,(H3,9,12,13)/b11-4+ |
InChI key | XMYKNCNAZKMVQN-NYYWCZLTSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS06 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H301 - H315 - H319 - H335 |
Precautionary Statements | P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
Hazard Classifications【危险分类】 | Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
Target Organs【靶器官】 | Respiratory system |
Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |