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Valganciclovir Hydrochloride
产品编号:3258381
规格:Pharmaceutical Secondary Standard; Certified Reference Material
CAS NO:175865-59-5
包装规格:1 G
产品类别:进口试剂
品牌:Supelco
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
32583811 G1670
产品别名

175865-59-5

盐酸缬更昔洛韦

Valganciclovir Hydrochloride

Valganciclovir hydrochloride hydrate

L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester, monohydrochloride hydrate

2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-amino-3-methylbutanoate hydrochloride hydrate

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C14H22N6O5·HCl · xH2O
Molecular weight
390.82 (anhydrous basis)
NACRES
NA.24
General description【一般描述】
Valganciclovir Hydrochloride is the L-valyl ester of ganciclovir and an antiviral drug, widely used to treat cytomegalovirus infections.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
Application【应用】
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Valganciclovir Hydrochloride may be used as a secondary pharma standard for the quantification of the analyte in pharmaceutical formulations using liquid chromatography technique.
Biochem/physiol Actions【生化/生理作用】
Valganciclovir hydrochloride hydrate is an antiviral used to treat cytomegalovirus infection. It is the prodrug of ganciclovir, a synthetic analog of 2′-deoxy-guanosine which is phosphorylated to a dGTP analog that competitively inhibits the incorporation of dGTP by viral DNA polymerase.
Analysis Note【分析说明】
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Other Notes【其他说明】
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote【附注】
To see an example of a Certificate of Analysis for this material enter LRAA5295 in the slot below. This is an example certificate only and may not be the lot that you receive.
产品性质
Quality Level【质量水平】
300
grade【等级】
certified reference material
pharmaceutical secondary standard
CofA
current certificate can be downloaded
packaging【包装】
pkg of 1 g
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format【格式】
neat
pharmacopeia traceability【药典可追溯性】
traceable to USP 1708004
storage temp.【储存温度】
2-8℃
SMILES string
O.Cl.CC(C)[C@H](N)C(=O)OCC(CO)OCn1cnc2C(=O)N=C(N)Nc12
InChI
1S/C14H22N6O5.ClH.H2O/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22;;/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22);1H;1H2/t8?,9-;;/m0../s1
InChI key
XASVRRIYQZVANH-AHBBCRTASA-N
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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