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托芬那酸
Tolfenamic Acid
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3253448 | 5 G | 1110 |
产品别名
13710-19-5
托芬那酸
Tolfenamic Acid
2 (3-Chloro-2-methylanilino)benzoic acid
2-([3-Chloro-2-methylphenyl]amino)benzoic acid
2-(3-氯-2-甲基苯胺)苯甲酸
2-([3-氯-2-甲苯基]氨基)苯甲酸
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C14H12ClNO2 |
Molecular weight | 261.70 |
EC number【EC 号】 | 237-264-3 |
MDL number | MFCD00133865 |
PubChem Substance ID【PubChem化学物质编号】 | 24899896 |
NACRES | NA.77 |
General description【一般描述】 | Tolfenamic acid is a fenamate and is made up of a monocarboxylate diphenylamine nucleus. |
Application【应用】 | Tolfenamic acid has been used in Arabidopsis bud assay for activity comparison with quinazolinedione derivatives (QADD) based compounds. |
Biochem/physiol Actions【生化/生理作用】 | Tolfenamic acid is involved in the inhibition of prostaglandin synthesis. It also plays a role in apoptosis of head and neck cancer cells. Non-steroidal anti-inflammatory agent. Interferes with synthesis of β-amyloid precursor protein, and thus Aβ peptides, by promoting degradation of an essential transcription factor. |
产品性质
Quality Level【质量水平】 | 200 |
Assay【测定】 | ≥98% (TLC) |
form【形式】 | powder |
solubility【溶解性】 | ethanol: 50 mg/mL, clear, greenish-yellow |
SMILES string | Cc1c(Cl)cccc1Nc2ccccc2C(O)=O |
InChI | 1S/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/h2-8,16H,1H3,(H,17,18) |
InChI key | YEZNLOUZAIOMLT-UHFFFAOYSA-N |
packaging【包装】 | 5 g in glass bottle |
安全信息
Pictograms【象形图】 | GHS06 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H301 |
Precautionary Statements | P301 + P310 |
Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |