特比萘芬 盐酸盐

C₂₁H₂₅N · HCl

327.89

MFCD00145430

329823287

NA.24

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards. Terbinafine hydrochloride is an antifungal drug. Its mode of action involves the inhibition of squalene epoxidase enzyme, an essential component of fungal cell systems involved in ergosterol biosynthesis.
烯丙胺衍生物。

Terbinafine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in drug dosage forms by UV spectrophotometry and high-performance thin layer chromatography (HPTLC).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

作用方式：抑制角鲨烯环氧酶，防止麦角甾醇的生物合成。
抗菌谱：抗真菌和抗真菌。抗皮肤细胞和一些酵母的杀真菌剂；抗真菌白色念珠菌。

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC3257 in the slot below. This is an example certificate only and may not be the lot that you receive.

300

certified reference material
pharmaceutical secondary standard

current certificate can be downloaded

HPLC: suitable
gas chromatography (GC): suitable

pharmaceutical (small molecule)

neat

traceable to PhEur Y0000535
traceable to USP 1643496

2-30℃

Cl[H].[H]\C(CN(C)Cc1cccc2ccccc12)=C(\[H])C#CC(C)(C)C

1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;

BWMISRWJRUSYEX-SZKNIZGXSA-N

GHS07,GHS09

Warning

H315 - H319 - H335 - H410

P261 - P273 - P305 + P351 + P338 - P501

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Respiratory system

13 - Non Combustible Solids

WGK 3