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ST247
产品别名
1356497-91-0
ST247
3-[[[4-(Hexylamino)-2-methoxyphenyl]amino]sulfonyl]-2-thiophenecarboxylic acid methyl ester
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C19H26N2O5S2 |
Molecular weight | 426.55 |
PubChem Substance ID【PubChem化学物质编号】 | 329825419 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | ST247 is a PPAR β/δ selective inverse agonist. The compound is based on the structure of GSK0660, and is 10-fold more potent in blocking the transcription of endogenous target genes: ST247 IC50 = 19 nm vs. GSK0660 IC50 = 210 nM. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 10 mg/mL (clear solution) |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | CCCCCCNc1ccc(NS(=O)(=O)c2ccsc2C(=O)OC)c(OC)c1 |
InChI | 1S/C19H26N2O5S2/c1-4-5-6-7-11-20-14-8-9-15(16(13-14)25-2)21-28(23,24)17-10-12-27-18(17)19(22)26-3/h8-10,12-13,20-21H,4-7,11H2,1-3H3 |
InChI key | MRWCGEOYGFZZCJ-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |