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SMER28
| 产品编号： | 3240494 |
| 规格： | >99% (HPLC), solid |
| CAS NO： | 307538-42-7 |
| 包装规格： | 5 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3240494 | 5 MG | 1800 | |||
| 3240494 | 25 MG | 7400 |
产品别名
307538-42-7
SMER28
6-Bromo-N-2-propenyl-4-quinazolinamine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H10BrN3 |
| Molecular weight | 264.12 |
| MDL number | MFCD02166825 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824598 |
| NACRES | NA.77 |
| Application【应用】 | SMER28 may be used in mTOR-mediated signaling studies. |
| Biochem/physiol Actions【生化/生理作用】 | SMER28 is a small molecule modulator of mammalian autophagy; enhances A53T alpha-synuclein clearance in PC-12 cells independent of rapamycin treatment; appears to act independent of the mTOR pathway, but combined treatment with saturating rapamycin concentration enhances the effect of either compound alone on A53T alpha-synuclein clearance; autophagy inducers may prove useful in the treatment of neurodegenerative and infectious diseases and cancer. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | >99% (HPLC) |
| form【形式】 | solid |
| solubility【溶解性】 | DMSO: >20 mg/mL H2O: insoluble |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Brc1ccc2ncnc(NCC=C)c2c1 |
| InChI | 1S/C11H10BrN3/c1-2-5-13-11-9-6-8(12)3-4-10(9)14-7-15-11/h2-4,6-7H,1,5H2,(H,13,14,15) |
| InChI key | BCPOLXUSCUFDGE-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
