Rabbit anti-Chk1 Antibody, Affinity Purified

NA.41

The epitope recognized by PLA0085 maps to a region between residues 250 and 300 of human Checkpoint Kinase 1 using the numbering given in SwissProt entry O14757 (GeneID 1111).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c.

rabbit

100

affinity purified immunoglobulin

primary antibodies

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human

immunohistochemistry: 1:1,000- 1:5,000
immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:1,000-1:5,000

O14757

wet ice

2-8℃

rabbit ... Chk1(1111)

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12 - Non Combustible Liquids

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