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Purvalanol A

产品编号:3211054
规格:≥98% (HPLC), powder
CAS NO:212844-53-6
包装规格:1 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
32110541 MG1840
产品别名

212844-53-6

Purvalanol A

2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine

NG-60

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C19H25ClN6O
Molecular weight
388.89
MDL number
MFCD02179211
PubChem Substance ID【PubChem化学物质编号】
24898543
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
Purvalanol A is found to inhibit ABCG2 (ATP-binding cassette G2) transporter in vitro. It is also known to attenuate cellular Src kinase action and induce cell cycle arrest at the G2 to M phase transition.
Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor.
Features and Benefits【特点和优势】
This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
产品性质
Quality Level【质量水平】
200
Assay【测定】
≥98% (HPLC)
form【形式】
powder
solubility【溶解性】
methylene chloride: 50 mg/mL
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
SMILES string
CC(C)[C@H](CO)Nc1nc(Nc2cccc(Cl)c2)c3ncn(C(C)C)c3n1
InChI
1S/C19H25ClN6O/c1-11(2)15(9-27)23-19-24-17(22-14-7-5-6-13(20)8-14)16-18(25-19)26(10-21-16)12(3)4/h5-8,10-12,15,27H,9H2,1-4H3,(H2,22,23,24,25)/t15-/m0/s1
InChI key
PMXCMJLOPOFPBT-HNNXBMFYSA-N
packaging【包装】
1 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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