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Purvalanol A
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3211054 | 1 MG | 1840 |
产品别名
212844-53-6
Purvalanol A
2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine
NG-60
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C19H25ClN6O |
Molecular weight | 388.89 |
MDL number | MFCD02179211 |
PubChem Substance ID【PubChem化学物质编号】 | 24898543 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | Purvalanol A is found to inhibit ABCG2 (ATP-binding cassette G2) transporter in vitro. It is also known to attenuate cellular Src kinase action and induce cell cycle arrest at the G2 to M phase transition. Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor. |
Features and Benefits【特点和优势】 | This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
Quality Level【质量水平】 | 200 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
solubility【溶解性】 | methylene chloride: 50 mg/mL |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
SMILES string | CC(C)[C@H](CO)Nc1nc(Nc2cccc(Cl)c2)c3ncn(C(C)C)c3n1 |
InChI | 1S/C19H25ClN6O/c1-11(2)15(9-27)23-19-24-17(22-14-7-5-6-13(20)8-14)16-18(25-19)26(10-21-16)12(3)4/h5-8,10-12,15,27H,9H2,1-4H3,(H2,22,23,24,25)/t15-/m0/s1 |
InChI key | PMXCMJLOPOFPBT-HNNXBMFYSA-N |
packaging【包装】 | 1 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |