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NVP-231
产品别名
362003-83-6
NVP-231
adamantane-1-carboxylic acid (2-benzoylamino-benzothiazol-6-yl)amide
N-[2-(benzoylamino)-6-benzothiazolyl]-Tricyclo[3.3.1.13,7]decane-1-carboxamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C25H25N3O2S |
| Molecular weight | 431.55 |
| MDL number | MFCD01988824 |
| PubChem Substance ID【PubChem化学物质编号】 | 329818618 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Ceramide kinase presents an attractive target for drug development because of its involvement in cell growth and inflammation. CerK biology is still poorly understood thus discovery and availability of inhibitors will facilitate research at this area. NVP-231 is a newly discovered potent, specific and reversible CerK inhibitor that competitively inhibits binding of ceraminde to CerK. |
| Features and Benefits【特点和优势】 | This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to off-white |
| solubility【溶解性】 | DMSO: >10 mg/mL |
| originator【创始人】 | Novartis |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C(Nc1nc2ccc(NC(=O)C34C[C@H]5C[C@H](C[C@H](C5)C3)C4)cc2s1)c6ccccc6 |
| InChI | 1S/C25H25N3O2S/c29-22(18-4-2-1-3-5-18)28-24-27-20-7-6-19(11-21(20)31-24)26-23(30)25-12-15-8-16(13-25)10-17(9-15)14-25/h1-7,11,15-17H,8-10,12-14H2,(H,26,30)(H,27,28,29)/t15-,16+,17-,25- |
| InChI key | MVSSJPGNLQPWSW-CIRRPZLZSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | nwg |
