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Notch-1 from mouse
| 产品编号： | 3175993 |
| 规格： | recombinant, expressed in E. coli, ≥95% (SDS-PAGE) |
| 包装规格： | 25 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Notch-1 from mouse
mT14
Neurogenic Locus Notch Homolog Protein 1
Notch A
p300
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins. |
| Physical form【外形】 | Lyophilized with PBS. |
| Reconstitution【重悬】 | Reconstitute with sterile water to 1 mg/mL. |
产品性质
| biological source【生物来源】 | mouse |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥95% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | calculated mol wt ~85.0 kDa (The extracellular domain of mouse Notch-1 (aa 19-488) (12 epidermal growth factor-like (EGF) repeats)) |
| packaging【包装】 | pkg of 25 μg |
| impurities【杂质】 | <0.1 EU/μg endotoxin (LAL test) |
| UniProt accession no.【UniProt登记号】 | Q01705 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... NOTCH1(18128) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
