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NO-1886
产品别名
133208-93-2
NO-1886
Diethyl 4-[(4-bromo-2-cyanophenyl)carbamoyl]benzylphosphonate
OPF 009
Ibrolipim
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C19H20BrN2O4P |
Molecular weight | 451.25 |
MDL number | MFCD00897807 |
PubChem Substance ID【PubChem化学物质编号】 | 329818584 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | Lipoprotein lipase activator. Overexpression of lipoprotein lipase in transgenic rabbits leads to increased small dense LDL in plasma and promotes atherosclerosis. Long-term administration of NO-1886 protects against the development of experimental atherosclerosis in animals. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | off-white to pale yellow |
solubility【溶解性】 | DMSO: ≥20 mg/mL |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | CCOP(=O)(Cc1ccc(cc1)C(=O)Nc2ccc(Br)cc2C#N)OCC |
InChI | 1S/C19H20BrN2O4P/c1-3-25-27(24,26-4-2)13-14-5-7-15(8-6-14)19(23)22-18-10-9-17(20)11-16(18)12-21/h5-11H,3-4,13H2,1-2H3,(H,22,23) |
InChI key | KPRTURMJVWXURQ-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle Packaged under nitrogen |
安全信息
Pictograms【象形图】 | GHS06 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H301 |
Precautionary Statements | P301 + P310 |
Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |