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NH125
产品别名
278603-08-0
NH125
1-Benzyl-3-cetyl-2-methylimidazolium iodide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H45IN2 |
| Molecular weight | 524.56 |
| MDL number | MFCD07370143 |
| PubChem Substance ID【PubChem化学物质编号】 | 329818598 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | NH125 exhibits anti-proliferation activity against many cancer cells. It also exhibits antibacterial effects by inhibiting bacterial histidine protein kinase. NH125 is a novel plant histidine kinase inhibitor and selective mammalian eurkaryotic elongation factor-2 kinase (eEF-2K). |
| Analysis Note【分析说明】 | IC50 = 60 nM for eEF-2 kinase vs protein kinase C (IC50= 7.5 μM), protein kinase A (IC50= 80 μM), and calmodulin-dependent kinase II IC50 > 100 μM). |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | white to off-white |
| mp | 88.2-94.9 ℃ |
| solubility【溶解性】 | DMSO: >20 mg/mL |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | [I-].CCCCCCCCCCCCCCCC[n+]1ccn(Cc2ccccc2)c1C |
| InChI | 1S/C27H45N2.HI/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-28-23-24-29(26(28)2)25-27-20-17-16-18-21-27;/h16-18,20-21,23-24H,3-15,19,22,25H2,1-2H3;1H/q+1;/p-1 |
| InChI key | RVWOHCBHAGBLLT-UHFFFAOYSA-M |
| packaging【包装】 | 5, 25 mg in glass bottle 在氮气保护下封装。 |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
