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Nepafenac
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3172936 | 10 MG | 840 | |||
3172936 | 50 MG | 3260 |
产品别名
78281-72-8
Nepafenac
2-Amino-3-benzoyl-benzeneacetamide
AL 6515
AHR 9434
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C15H14N2O2 |
Molecular weight | 254.28 |
MDL number | MFCD08067732 |
PubChem Substance ID【PubChem化学物质编号】 | 329825296 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) that is routinely used in opthamology to control pain following cataract surgery. Nepafenac, a prodrug of amfenac, is used in the treatment of diabetic retinopathy. It is metabolized to its active form through intraocular enzymatic hydrolysis. Nepafenac has a molecular weight of 254.28 kDa and effectively penetrates through the cornea. Its molecule structure enables nepafenac to possess better permeability. Nepafenac has a low inhibitory effect on cyclooxygenase. |
产品性质
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | faintly yellow to dark yellow |
solubility【溶解性】 | DMSO: ≥5 mg/mL |
storage temp.【储存温度】 | room temp |
SMILES string | NC(=O)Cc1cccc(c1N)C(=O)c2ccccc2 |
InChI | 1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18) |
InChI key | QEFAQIPZVLVERP-UHFFFAOYSA-N |
Gene Information | human ... PTGS1(5742), PTGS2(5743) |
packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS09 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H400 |
Precautionary Statements | P273 |
Hazard Classifications【危险分类】 | Aquatic Acute 1 |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |