Monoclonal Anti-TDG antibody produced in mouse

NA.41

Recombinant protein encompassing a sequence within the center region of human TDG.

Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq]

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Purification: Affinity purified by Protein A

Phosphate-buffered saline, no preservative added.

100

mouse

unconjugated

affinity isolated antibody

primary antibodies

GT311, monoclonal

buffered aqueous solution

46kDa

human

1mg/mL

western blot: 1:500-1:3000

IgG2a

Q13569

wet ice

−20℃

human ... TDG(6996)

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

12 - Non Combustible Liquids

WGK 1