Monoclonal Anti-Rin/Rit2 antibody produced in mouse

NA.41

Rin/Rit2 (Ras-like without CAAX 2) belongs to the Ras superfamily of small guanosine triphosphatases. In human, it is expressed in several neurons whereas in mouse, it is expressed in the ganglion cell layer and inner nuclear layer of the retina. It is located on human chromosome 18q12.3.

recombinant human Rin.

Aberrations in Rin/Rit2 (Ras-like without CAAX 2) causes parkinson′s disease. It participates in neurotrophin signaling. It trigger ERK (extracellular signal-regulated kinase) and p38 MAP (mitogen-activated protein) kinase signaling to promote differentiation.

Solution in 20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, and 3 mM sodium azide.

200

mouse

unconjugated

purified immunoglobulin

primary antibodies

18G4(27G2), monoclonal

buffered aqueous glycerol solution

antigen ~36 kDa

human, mouse

~1 mg/mL

western blot: 1:5,000 using HEK293 cells expressing HA-tagged Rit

IgG2b

Q99578

wet ice

−20℃

human ... RIT2(6014)
mouse ... Rit2(19762)

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