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Monoclonal Anti-MTRR antibody produced in mouse
产品编号: | 3148758 |
规格: | clone 1G7, purified immunoglobulin, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Monoclonal Anti-MTRR antibody produced in mouse
Anti-MSR
Anti-5-methyltetrahydrofolate-homocysteine methyltransferase reductase
基本信息
NACRES | NA.41 |
General description【一般描述】 | Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. (provided by RefSeq) |
Immunogen【免疫原】 | MTRR (NP_002445, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MRRFLLLYATQQGQAKAIAEEMCEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKI |
Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
Legal Information【法律信息】 | GenBank is a registered trademark of United States Department of Health and Human Services |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 1G7, monoclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
technique(s) | indirect ELISA: suitable western blot: 1-5 μg/mL |
isotype【同位素/亚型】 | IgG2aκ |
GenBank® accession no. | NM_002454 |
UniProt accession no.【UniProt登记号】 | Q9UBK8 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... MTRR(4552) |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |