Monoclonal Anti-Monocyte Chemotactic Protein-2 antibody produced in mouse

MFCD01092422

NA.41

Monocyte Chemotactic Protein-2 (MCP-2) belongs to a family of C-C chemotactic cytokines. MCP-1, -3, -4, and -5 are the other five monocyte chemo attractants identified. The MCP cytokines are involved in recruitment of leukocytes to the sites of inflammation, and activate NK cells and CD4+ and CD8+ T lymphocytes. Additionally, MCP cytokines can activate basophils to secrete histamines and also attract eosinophils. MCPs play an important role in pathological conditions such as systemic sclerosis, myocardia and cardiac ischemia. Anti-monocyte chemotactic protein 2 antibody specifically reacts with human MCP-2. The antibody shows <20% cross reactivity with recombinant human MCP-1 and recombinant mouse MIP-1α.

Neutralizes the biological activity of recombinant human MCP-2. Shows <20% cross-reactivity with recombinant human MCP-1 and recombinant mouse MIP-1α.

recombinant human MCP-2 expressed in E. coli.

Monoclonal Anti-Monocyte Chemotactic Protein-2 antibody may be used in ELISA at a concentration of 2.0 μg/ml. For immunoblotting a working concentration of 1-2 μg/ml may be used. The antibody is suitable for neutralization reactions; ND50 is 1-4 μg/ml.

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose

Purified using protein A.

200

mouse

unconjugated

purified immunoglobulin

primary antibodies

35509.11, monoclonal

lyophilized powder

human

indirect ELISA: suitable
neutralization: suitable
western blot: suitable

IgG1

P80075

−20℃

human ... CCL8(6355)

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13 - Non Combustible Solids

WGK 3