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Monoclonal Anti-Monocyte Chemotactic Protein-1 antibody produced in mouse
产品编号: | 3148602 |
规格: | clone 24822, purified immunoglobulin, lyophilized powder |
包装规格: | 0.5 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Monoclonal Anti-Monocyte Chemotactic Protein-1 antibody produced in mouse
Anti-MCP-1
Anti-CCL2
基本信息
MDL number | MFCD00282367 |
General description【一般描述】 | Monocyte Chemotactic Protein-1 (MCP-1) is a chemotactic factor that belongs to CC chemokine family and can attract basophils and monocytes but not eosinophils or neutrophils. It is produced in keratinocytes, fibroblasts, hepatoma cells and Type II pneumocytes in response to IL-1. It has a crucial role in recruiting immune cells to the site of antigens as well as behaves as an inflammatory mediator which stimulates the directional migration of T cells and monocytes. Monoclonal anti-Monocyte Chemotactic Protein-1 antibody is suitable for neutralization, in which it will not neutralize the activity of recombinant human MIP-1α, recombinant mouse MIP-1α or recombinant human RANTES. Mouse anti-Monocyte Chemotactic Protein-1 antibody reacts specifically with human MCP-1/CCL2. |
Specificity【特异性】 | The antibody will neutralize the biological activity of recombinant human MCP-1.This antibody does not exhibit cross-reactivity with recombinant human RANTES, recombinant human MIP-1α, or recombinant mouse MIP-1α.. |
Immunogen【免疫原】 | recombinant human MCP-1/CCL2 expressed in E. coli. |
Application【应用】 | Monoclonal anti-Monocyte Chemotactic Protein-1 antibody can be used in western blotting. |
Physical form【外形】 | Lyophilized from a 0.2 μm solution in phosphate buffered saline containing carbohydrates. |
Preparation Note【制备说明】 | Purified using protein A. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 24822, monoclonal |
form【形式】 | lyophilized powder |
species reactivity | human |
technique(s) | neutralization: suitable western blot: suitable |
isotype【同位素/亚型】 | IgG1 |
UniProt accession no.【UniProt登记号】 | P13500 |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... CCL2(6347) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 2 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |