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Monoclonal Anti-MATK, (C-terminal) antibody produced in mouse

产品编号:3148230
规格:clone 2C5, purified immunoglobulin, buffered aqueous solution
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
314823050 μG5040
产品别名

Monoclonal Anti-MATK, (C-terminal) antibody produced in mouse

CTK

HYL

CHK

DKFZp434N1212

LSK

HYLTK

MGC1708

HHYLTK

MGC2101

基本信息
NACRES
NA.41
General description【一般描述】
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. (provided by RefSeq)
Immunogen【免疫原】
MATK (NP_647612, 422 a.a. ~ 507 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
RAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLARELRSAGAPASVSGQDADGSTSPRSQEP
Physical form【外形】
Solution in phosphate buffered saline, pH 7.4
产品性质
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
2C5, monoclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen ~35.57 kDa
species reactivity
human
technique(s)
indirect ELISA: suitable
western blot: 1-5 μg/mL
isotype【同位素/亚型】
IgG2aκ
NCBI accession no.【NCBI登记号】
NM_139355
UniProt accession no.【UniProt登记号】
P42679
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... MATK(4145)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 1
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