Monoclonal Anti-m/μ Calpain, Small Subunit antibody produced in mouse

MFCD01864149

NA.41

Calpain small subunit 1 (Capns1) is a small regulatory subunit associated with the μ-calpain (calpain 1) and m-calpain (calpain 2). The CAPNS1 gene is mapped to human chromosome 19q13.12.

purified calpain from human placenta.

Monoclonal Anti-m/μ Calpain, Small Subunit antibody produced in mouse has been used in immunoprecipitation and immunoblotting.

Calpain small subunit 1 (Capns1) participates in the actin cytoskeleton rearrangement and cell migration events. It is crucial for embryonic development. Capns1 interacts with the Ras GTPase activating protein Src homology 3 domain (SH3) (RasGAP-SH3) domain to regulate cell migration and cell survival. It is essential for calpain activity. Capns1 is associated with the oncogenesis of many tumor types including hepatocellular, colorectal, ovarian, and breast cancer.

Solution in 0.02 M sodium phosphate, pH 7.5, and 0.15 M sodium chloride containing 50% glycerol and 3 mM sodium azide.

200

mouse

unconjugated

purified immunoglobulin

primary antibodies

28F3, monoclonal

buffered aqueous glycerol solution

antigen 28-30 kDa

human, bovine

~1 mg/mL

immunoprecipitation (IP): suitable
western blot: 1:5,000 using normal human fibroblasts or MDBK cells

IgG1

Q96L46

wet ice

−20℃

human ... CAPNS1(826), CAPNS2(84290)

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12 - Non Combustible Liquids

WGK 1